Sentence examples for reduced editing from inspiring English sources

Thus, several species tolerate reduced editing of rpoA C200 in contrast to clpP C559.

Pin1−/− mouse embryonic fibroblasts show mislocalization of ADAR2 in the cytoplasm and reduced editing at the GluR2 Q/R and R/G sites.

Consistent with these results, a reduction in PLS genes (Table  5) in Geraniaceae was detected, where reduced editing frequency was previously demonstrated [ 1].

Decrease in another member of this family, ADAR2, is thought to underlie excitotoxic loss of motor neurons in ALS via reduced editing of AMPA receptors subunits [ 51].

Reduced editing can either be caused by the degeneration of nuclear-encoded editing factors or plastidial cis-elements that direct the editing machinery.

Reduced editing results in acute neurodegeneration in mice and, accordingly, defective editing was detected in motor neurons of individuals affected by sporadic ALS [159].

The idea behind the regional hubs, which mimic an overhaul of The A.P.'s foreign operations earlier in the decade, is to reduce editing gridlock at its major filing desks, including that in New York.

Inhibition of mir-376 cluster processing in the brain may be relevant but the mutant protein would also probably bind RNA editing target sites such as the Q/R editing site in the GluR-B transcript and reduce editing by ADAR2 and ADAR1 at this site.

Finally, the use of short homology arms does not reduce edit frequency even for gene-sized insertions like GFP.

This comparative transcriptome analysis of G. maderense and P. x hortorum detected a reduction in PPR proteins associated with RNA editing, which corresponds with reduced RNA editing in the mitochondria.

To rule out the possibility that dsRNA accumulation in human cells results from decreased ADAR2 function, we asked whether knocking down TDP-43 in human M17 neuroblastoma cells led to reduced GluR2 Q607R editing, an ADAR2-specific editing site (Nishikura, 2010).