Sentence examples for reduced dosage of from inspiring English sources

It should be noted though, that reduced dosage of Dyrk1A did not completely prevent spatial learning, as indicated by the initial trials of the place acquisition task.

Our study also suggests that administration of TGFβ antagonists during chemotherapy may sensitize carcinoma cells, in part through the inhibition of EMT, to the anti-tumor and anti-metastatic activities of chemotherapy resulting in increased therapeutic efficacy and reduced dosage of chemotherapeutics and their unwanted side effects.

Establishment of sister chromatid cohesion in meiosis in yeast may therefore be more sensitive to reduced dosage of Ctf7 than in mitosis.

It enabled the provision of velaglucerase alfa, an investigational drug at the time, to patients with GD1 who were faced with an interruption, delay, or reduced dosage of imiglucerase.

Our data indicate that, under these experimental conditions, reduced dosage of the ancestral Ins2 gene can provide protection against obesity similar to that gained by reducing the dosage of rodent-specific Ins1 [ 11].

> -wrap-foot> FHH3 is associated with heterozygous loss-of-function AP2σ2 mutations, and these could be causing the disease by either haploinsufficiency (i.e. a reduced dosage of the wild-type AP2σ2 protein) or dominant-negative effects on the heterotetrameric AP2 complex.

Only 3 patients (13.6%) had delayed chemotherapy and only 3 (13.6%) reduced dosages of MTX.

Furthermore, reduced dosages of both drugs achieved maximal cytotoxic effects by combining TPT with CHEK1 inhibitor.

In contrast, reducing dosage of anaerobic organisms resulted low removal of NH3 N.

The abnormal morphology of the PGCs was indeed caused by elevated CP110, as this phenotype could be partially suppressed by reducing dosage of the CP110 gene.

Moreover, several studies have suggested that continuous interventions (combined diet and exercise) can improve the plasma glucose level and reduce dosage of hypoglycemic agents.