Exact(3)
Finally, we showed that in vitro lipoteichoic-acid-stimulated neutrophils adoptively transferred into naïve WT mice display a significantly reduced competence to migrate into the perinoneal cavity in response to thioglycolate.
Finally, we showed that in-vitro lipoteichoic acid-stimulated neutrophils adoptively transferred into naïve WT mice display a significantly reduced competence to migrate into peritoneal cavity in response to thioglycolate.
No differences of CD45.1+ donor-derived BM cells were found among 2- and 8-month-old CD45.2+ IL7R−/− hosts, whereas, 8-month-old CD45.2+ IL7R−/− thymic niches have already exhibited a significantly reduced competence to support CD45.1+ donor thymocyte development (Fig. 5C, and Supplemental Figs. S3B and C right panel).
Similar(57)
Functional decline of the hematopoietic system occurs during aging and contributes to clinical consequences, including reduced competence of adaptive immunity and increased incidence of myeloid diseases.
Reduced competence in medication self-administration is associated with higher risk of hospitalisation and requirement for assisted living [ 3- 5].
Despite being derived from postimplantation embryos, EpiSCs have reduced competence for the germline fate (Hayashi and Surani, 2009).
These perturbations culminate in clinically significant consequences, including reduced competence of adaptive immunity (Linton & Dorshkind, 2004) and increased incidence of myeloid diseases (Lichtman & Rowe, 2004).
Very recently, reduced oocyte competence to development was reported in frozen cycles when compared with sibling fresh cycles (Magli et al., 2009), confirming the negative impact of slow-freezing procedure on oocyte potentiality.
Therefore, both the protective activity of hemodialysis on the course of HCV infection and attenuated inflammatory reactions in the liver due to reduced immune competence of chronic uremic patients may be plausible factors reducing hepatocyte destruction, which reflected by the ALT levels.
Her enemies wrote her history, reducing her shrewd politics and managerial competence to sexual manipulation.
In this study, chronic handling stress appeared to cause reduced immune competence as evidenced by the decreased survival of isolated macrophages from stressed fish (compared with macrophages from control, non-stressed fish) following incubation with A. salmonicida [ 48].
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