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On a subcellular level we noted (1) a significant increase of cytoplasmic CAR in neoplastic tissues compared with the normal mucosa, (2) reduced CAR presence at the plasma membrane in primary cancers, and (3) a 're-localisation' of CAR to the plasma membrane in metastatic tumours.
Western blotting confirmed reduced CAR protein expression in all cell lines after stable transfection of a CAR-specific siRNA and increased CAR protein levels following ectopic expression of hCARcDNA.
Western blotting confirmed reduced CAR protein expression in AGS cells upon stable transfection of CAR-specific siRNA, whereas ectopic expression of hCARcDNA in MKN28 and MKN45 cells resulted in a marked increase of CAR protein levels.
Although the evidence is limited, "car clubs," in which car drivers hire cars for short periods rather than owning them outright, are reported to have reduced car mileage (by 33% in The Netherlands), increased cycling, and reduced motor vehicle ownership.
More specifically, PSD patients may show exaggerated CAR according to the general finding of hypercortisolemia in acute stroke patients, or reduced CAR according to some studies mentioned above.
Sustrans' TravelSmart programme provides tailored travel advice direct to households and has reduced car use by more than 10% in the towns and cities where it has operated.
Similar(40)
They want to reduce car use, period.
Furthermore, it benefits the environment by reducing car usage.
Many cities are also committed to reducing reducing car traffic and diesel vehicles in particular.
Completion of driver's ed helps reduce car insurance payments, usually about 10percentt.
So how can Hanoi succeed in reducing car usage where Beijing has not?
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