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While proteasome and macroautophagy inhibitors reduce turnover of mHDx-1, Happ1 is still able to reduce mHDx-1 under these conditions, indicating Happ1-accelerated mHDx-1 clearance does not rely on these processes.
We show that mutations abrogating antiestablishment activity also reduce turnover of cohesin on pericentric chromatin.
We speculate that large aromatic residues might interact too strongly with Phe93 and thereby reduce turnover of the enzyme.
Similar(57)
Reduced turnover of lipids in fat cells [3] may lead to decreased adipocyte fatty acid trapping and elevated levels of circulating fatty acids, which in turn exacerbate the dyslipidemia [14], [15] (Fig. 4B).
Moreover, reduced turnover of dCREG could also be observed upon cathepsin L depletion in whole flies.
As the number of autophagosomes is frequently used to evaluate autophagy, the accumulation of them in the cytosol reflects increased formation of autophagosomes or reduced turnover of them.
However, they show reduced turnover of this transporter, correlating with its persistent presence at the plasma membrane and thus showing that didBΔ leads to a detectable trafficking phenotype.
However, because of its small size, 5HFA resides loosely in the binding site of the wild type enzyme (Additional file 7C), which explains its low affinity and reduced turnover of 5HFA compared with tricetin.
The possibility is discussed that the hyperalgesia noted above results from a permanently reduced turnover of brain serotonin produced by halothane present in brain at days 10-15 of gestation.
One of the main aims of this project was to determine the extent to which perceived organizational support influenced commitment of radiographers to the organization, to reduce turnover intent and quality of service rendered.
As discussed in the previous paragraph, this is a plausible finding for firms attempting to reduce turnover with the help of CVT.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com