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It is possible that replacement of the lipid component by a less toxic lipid will further reduce toxicity.
The NRF2-mediated oxidative stress response has been revealed to reduce toxicity and carcinogenesis during exposure to electrophile or other environmental toxicants or inflammation in mammalian models [34].
Therefore, alternative sources of L-ASNase may be useful to reduce toxicity and enhance efficacy.
Sarkar, S. et al. Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
A common one – higher surface reactivity – can be hugely beneficial when trying to increase the effectiveness of a treatment – to reduce toxicity, cost and the dose required.
Encapsulating artemisinin into poly lactic-co glycolic nanoparticles may improve its effectiveness and reduce toxicity.
This constrain has led to adsorption-based techniques that help immobilize the metals and reduce toxicity.
This selective targeting and local delivery would reduce toxicity to other tissues and pack a much bigger punch than current therapies.
As the hexavalent chromium had already been turned into the less dangerous trivalent chromium, and the baking process would also reduce toxicity, the idea was that this would remove any remnant pollution risks.
Our results showed that traditional processes could reduce toxicity as desired, but also led to more than 85.2% alkaloids loss.
Dyes are frequently combined with material substrates to modulate their properties, enhance stability, reduce toxicity, and improve delivery.
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