In conclusion, our results show that an increased frequency and a reduced time interval between injuries worsen headache behavior after mild closed head injury.
In the PRINCE study, induction of hypothermia with intranasal cooling devices in a prehospital setting may be useful in reducing time intervals required to cool the patients [ 13].
Classically, authors simply use filters generating orthogonal systems at the Nyquist rate (or below the Nyquist rate) and then reduce the time interval [4, 9] with a normalization factor.
In the field of blood stream infections real-time PCR based methods as SeptiFast® were engineered to supplement culture based methods of pathogen identification and to reduce the time interval of calculated anti-infective therapies.
The key is how to reduce the time interval from receipt of the 119 call to ROSC.
Taking this into account one can assume that it is possible to reduce the time interval for further one or two days.
In contrast, non-replicating vaccines, which are less likely to exhibit interference among the virus serotypes, could potentially reduce the time interval required between primary and booster vaccinations to induce protection more rapidly.
This suggests that a TFIID-TFIIB-DNA sub-complex is likely the most susceptible substrate for inhibition, while the presence of other core promoter factors may facilitate the progression of PIC assembly and reduce the time interval of this vulnerable stage.
This study showed that survival rates for patients with PCAS are increased with bystander CPR and special procedures by EMTs, but the results suggested it may be even more important to try to reduce the time interval to ROSC if the patient is to be a good neurological outcome.
Increasing calcium concentration and adding NPS R-467 in culture media for eUCM-MSC might be beneficial in order to obtain a desirable result of increasing the cell number and reducing the time interval necessary to obtain enough cells for downstream therapeutic purposes.
