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Cells lacking CaMKK ppk34 failed to accelerate mitosis and reduce their cell size to the same degree as wild-type cultures.
Additionally, for those herpesviruses with tropism to immune effector cells, it is of interest either to reduce the overall expression or to perturb the endosomal trafficking of immune recognition molecules (i.e., TCR/CD3, CD4 molecule, costimulatory molecules, adhesion molecules) and thereby, reduce their cell surface expression.
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Most tumors are initially noninvasive and gradually become more invasive as they reduce their cell-cell adhesiveness and (often) increase their cell-extracellular-matrix (ECM) adhesiveness [21].
Studies in primordial germ cells demonstrate that loss of HP1γ also reduces their cell number through impaired cell cycle progression [ 13].
Most oligotrophes achieve a high surface to volume ratio (s/v) by reducing their cell diameter; H. walsbyi does so by extremely flattening itself [ 11].
Hyaluronan has the capacity to make cells less adhesive, reducing their cell-cell contacts and thereby inducing them to separate from each other.
After switching on LAPC, the low-loaded cells reduce their s whereas cell no.11 does not change it.
In this region, due to the depolarization block, the inhibitory cells reduce their output, while the excitatory cells generate sufficient recurrent excitation to maintain a high level of activity.
When cultured in the absence of anchorage, for instance on polyhema-coated dishes, these cells reduce their growth rate and undergo programmed cell death [ 15].
Some people take vitamins to reduce their exposure to cell-wrecking free radicals.
It is generally recognized that serum proteins can bind to chemicals and reduce their availability to cells.
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