Sentence examples for reduce the variant from inspiring English sources

Hence, clinical and research users with prior knowledge of a disease are able to dramatically reduce the variant search space based on a wide variety of custom prioritization criteria.

Table S3, we reduced the variant count to less than 15 in all cases.

Exome sequencing in human medicine benefits from the availability of large databases of known SNPs, known pathogenic variants, and control genomes; during analysis variants found in these databases can generally be excluded when one is looking for novel variants, significantly reducing the variant pool.

As interpretation came to be seen as interpolation into or distortion of the text, the attempt was made to write texts in such a manner as to reduce the possibility of variant interpretations.

Because many variants are produced for a given sample, mechanistic and population genetic assumptions are often used to reduce the set of variants (Ng et al., 2009).

The next step is to reduce the number of variants by filtering.

To reduce the complexity, two variants of SDPDF approximations were analysed: a piecewise exponential fit and a lognormal fit.

Linkage information combined with NGS and filtering can reduce the number of variants for follow-up.

Another way to reduce the number of variants in a bin is to apply functional predictions.

The approach consists of two strategies that dramatically reduce the number of variants to be clinically considered in the first instance (Fig.  3).

To reduce the probable germline variants, the single nucleotide polymorphisms (SNPs) that were registered in the dbSNP and in-house Japanese SNP databases were eliminated.