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Messina accepts from the user the minimum sensitivity and specificity values that all classifiers (equivalently, genes) identified must satisfy, and therefore allows the experimenter to flexibly reduce the stringency of the gene selection process.
This reflects the consistency criterion built into the binding matrix definition; a larger input set of sequences generally tended to reduce the stringency of the classifier.
Toxoplasma could directly retard the fetal development or could shift the moment of the implantation of the blastocyst or reduce the stringency of embryo quality control, thus allowing fetuses with mild developmental disorders to escape it.
A nice feature of the algorithm is that probes can be assigned to each distribution with a certain probability, allowing us to increase or reduce the stringency of our assignments easily.
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Interestingly, election variables are generally non-significant, with the exception of the case of EPL reforms: the evidence suggests that reforms reducing the stringency of EPL reforms are more likely to be carried just after elections.
Reducing the stringency of the fold change cut-off in our analysis to 2.5 fold induction revealed that a zeaxanthin epoxidase gene (ABA1), which catalyses the first step of ABA biosynthesis, was also induced by dicamba.
Thus, by reducing the stringency of selection criteria for activity records, high average promiscuity rates were obtained.
Including fever and tachycardia as necessary symptoms to begin the algorithm, timing public health notification, and reducing the stringency of the requirement for an epidemiologic link were discussed.
This was further emphasised by reducing the stringency of the statistical analysis to p ≤ 0.08, which increased the number of genes detected by microarray specifically (not shown).
In some cases, reducing the stringency of filtering led to a disproportionate increase of the TP and, thus, to an increase of the PPV.
Reducing the stringency of FPC assembly (cutoff of 1 e-15) merged all six contigs associated with walk-134 into a single contig.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com