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Life is a very big thing, and to reduce the functionality of life to just one perception then you project it to the world.
It's not that retweets reduce the functionality of the trail of overlapping social circles, it's that they lock them behind the Wall.
To reduce the functionality of the RNA in the exosomes, we exposed the exosome fraction to UV-C radiation, as this treatment is known to have a damaging effect on nucleic acids [42] [44], [50].
For genes with a pattern of sexually antagonistic fitness effects, nonsynonymous mutations that reduce the functionality of the protein might be beneficial to males but harmful to females.
Similarly, if one assumes that the main effect of missense errors is to reduce the functionality of the protein produced, then the cost of these errors is expected to depend greatly on specific details such as the structural and functional role of the amino acid at which the error occurs and the physiochemical differences between the correct and the erroneously incorporated amino acids.
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These combat- and trauma-induced skeletal muscle injuries are characterized by volumetric muscle loss (VML), which significantly reduces the functionality of the injured muscle.
The dyes used in the photopolymerization process also reduced the functionality of the beta cells as insulin secretion decreased significantly with increasing dye concentration [44].
We hypothesize that binding of the anti-N-terminal antibody to ADM still allows receptor binding, but less efficiently, and thus reduces the functionality of ADM so that excess levels, which have been suggested to become harmful during the progression of sepsis, then get functionally neutralized to a certain limited extent.
It is likely that abnormal maturation of RBCs reduced the functionality of these cells and thus contributed to causing hypoxia.
In contrast, the A40V substitution that shows a similar reduction of total BicD phosphorylation, also greatly reduces the functionality of BicD.
In lieu of a spontaneous MA experiment, MA was independently accelerated in the experimental lines by simultaneously (i) bottlenecking populations, and (ii) reducing the functionality of the mismatch repair (MMR henceforth) gene msh-2 by RNAi knockdown [ 65].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com