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When some PPAEs are activated by immune-challenge, the serpins co-express to reduce the expression and activity of PPAEs.
Some COX-2 inhibitors (e.g., celecoxib) can reduce the expression of survivin.
One explanation could be that chronic alcohol exposure might reduce the expression and/or function of 5-HT1A heteroreceptors within the dentate gyrus, as previously described16.
To confirm that they got the right protein, the researchers used gene-silencing techniques to reduce the expression of cytokeratin 6A in the cornea of mice.
Hes1 binds directly to the E-boxes on δ-catenin promoter and can reduce the expression of δ-catenin in prostate cancer cells.
We used RNAi to reduce the expression of the five napin genes and deplete the seeds of this SSP.
LRR1 silencing does not reduce the expression of three rice receptor kinases or components of XA21-mediated immunity.
Furthermore, corticosteroids reduce the expression of NFκB-mediated pro-inflammatory cytokines, including IL-1, IL-6, and TNF-α [6].
Our previous experience with Raloxifene has documented its ability to reduce the expression of NF-κB making a plausible role for SERMs in management of IBD.
For instance, if BL21 is used to produce recombinant protein, failure to avoid these minimum codons may dramatically reduce the expression level.
We next introduced TrpC3-shRNA into these cells to reduce the expression of TrpC3.
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CEO of Professional Science Editing for Scientists @ prosciediting.com