Sentence examples for reduce technical variability from inspiring English sources
Intraindividual analysis of tumor and benign tissue samples (adjacent to tumor) from the same cancer patients may reduce technical variability and thus provide a means to increase specificity of the results and to increase chances to identify specific disease-associated protein alterations.
Labeled internal standards should be used to reduce technical variability (100– 100).
Even for the data with minor batch effects, it can further reduce technical variability on the top of normalization.
To compare the composition of the Dhh1 complex in the two different cell growth conditions, we analyzed pairs of Dhh1 GFP immunoisolations from −glucose and +glucose media detected by MS using the same instrument on the same day to reduce technical variability.
For one time point, all six replicates were run together, reducing technical variability.
This provides a replicated measurement for each hybridization that can be used for quality control and that reduces technical variability.
CSS is a semi-automated detection device, which importantly minimizes the source of technical failures and therefore reduces technical variability in comparison to a manual method.
RLM has also been used in the evaluation of peptide identifications [ 16], reducing technical variability in functional protein microarrays [ 17], and SILAC peptide ratio calculation [ 18].
RNA-seq offers a larger dynamic range of quantification, reduced technical variability, and higher accuracy for distinguishing and quantifying expression levels of homeologous copies than microarray [ 17].
To further test BMIQ, we used data on technical replicates (to show that it reduces technical variability) and matched BPS data (to show that it reduces the bias of type2 probe values).
We conclude that reducing technical variability between the samples and using bioinformatics tools that maximize statistical power of CNV detection, such as ExomeDepth, will allow efficient CNV identification and will increase the value of the future exome sequencing experiments.
