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(4) If statins are prescribed, use moderate doses that reduce plasma levels of low-density lipoprotein (LDL) cholesterol by ≥30%to40%0%.
It is licensed to reduce plasma levels of prolactin.
Loss of the RIIβ subunit has been shown to protect mice on a high-fat, high-carbohydrate diet against weight gain, hyperinsulinemia, fatty livers and insulin resistance, reduce plasma levels of VLDL and LDL cholesterol, and improve glucose dispersal [6].
Statins mainly reduce plasma levels of LDL, while having little effect on TG [ 7].
In patients with psoriatic arthritis, apremilast has been shown to reduce plasma levels of TNF- α, IL-6, and other pro-inflammatory cytokines and chemokines [ 43].
A single preemptive dose of IL-1 Ra was able to significantly reduce plasma levels of IL-1β at 6 and 24 hours.
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In the process, there are two different forms of protein C deficiencies: type I is accompanied by reduced synthesis of protein C thus reduced plasma levels, while type II is characterized by reduced protein C activity but normal plasma level.
Further, reduced plasma levels of MMP3 in SO/SOAE pre-treated animals suggest that one-month pre-treatment is quite effective in reducing matrix metalloproteinases.
Corsi, M. M. et al. Reduced plasma levels of P-selectin and L-selectin in a pilot study from Alzheimer disease: relationship with neuro-degeneration.
For instance, activated protein C in septic shock patients with impaired consciousness significantly reduced plasma levels of S100-β protein [93].
In a mouse model of pulmonary hypertension, administration of pravastatin ameliorated hypoxia-induced pulmonary hypertension and was associated with decreased accumulation of bone marrow-derived progenitor cells in the pulmonary artery adventitia and reduced plasma levels of CXCL12 [10].
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CEO of Professional Science Editing for Scientists @ prosciediting.com