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The purpose of this study was to evaluate the efficacy of two cost reducing methodologies, establishment of critical clinical pathways, and standardization of implant costs.
Ultimately, though cloning bias will reduce our methodology's effectiveness in some regions compared to simulation, this is a problem common to all sequencing methods that affects a small portion of the genome and is best handled during the finishing step.
The problems arising from degradation and contamination of the samples are much reduced in methodology such as next-generation sequencing (NGS) [ 31] or whole-genome sequencing (WGS) [ 32].
While it is not possible to discuss the use of statistics in detail, it is important to recognize that studies should be designed to answer an hypothesis and that the help of a statistician to design a study is likely to yield enormous benefits by reducing inappropriate methodology and bias [ 1].
Experimental results show that in comparison with the SRAM only L1 cache configuration, our hybrid cache configuration and data migration methodology reduce energy consumption by about 15 20%, with only nearly to 5% of latency overhead.
Thus the ADL-driven methodologies reduce time-to-market and enable generation of cost-effective and reliable embedded systems.
Quite simply, RRS methodologies reduce a genome's complexity by enriching, separating, or eliminating a portion of the genome prior to sequencing.
Despite the widely recognised importance of blinding endpoint reviewers in order to reduce bias, blinding methodologies are generally poorly reported [ 20, 21].
Because the FDR correction constitutes a conservative criterion (i.e., FDR methodologies reduce its statistical power as the number of tests increases [ Carvajal-Rodriguez et al. 2009]), the actual number of clusters under functional constraint is likely to be higher than these 58 cases.
In such we feel that such items do help draw attention of the readers to potential methodological limitations, and thus reduce assumptions that the methodology was sound.
System organization is a key methodology to reduce system complexity and to improve system efficiency.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com