Your English writing platform
Free sign upSuggestions(1)
Exact(3)
Insulin, glucose, glucocorticoids, and TNF-α appear to stimulate leptin secretion, whereas sympathetic and adrenergic stimulation, growth hormone, thyroid hormones, androgens, and melatonin appear to reduce leptin levels.
Rosenbaum and Leibel have shown that controlled 10% weight loss in an experimental setting is sufficient to reduce leptin levels and is associated with decreased SNA (Rosenbaum et al., 2005).
These lead to inflammation and reduce leptin levels overall.[4].
Similar(57)
Fasting reduces leptin levels [ 12], and severe calorie restriction with weight loss reduces circulating RBP4 [ 13].
Leptin levels are also modulated by C/EBPβ, and mice lacking C/EBPβ have severely reduced leptin levels [ 27].
The inhibition of leptin signaling therefore almost completely blocked VEGF expression and reduced leptin levels within MCF-7 BC.
In addition, greater circulating IL-6 levels and reduced leptin levels were observed in complicated SABSI compared to uncomplicated SABSI.
33 Observational epidemiological studies have also shown reduced leptin levels, after controlling for BMI or adiposity, in habitual short sleepers.
Furthermore, reducing leptin levels in obASCs also resulted in a reduction in tumor volume and fewer metastatic lesions in the lung and liver of SCID/beige mice.
Curiously, at the age of 8 weeks, mice overexpressing Fto had reduced leptin levels after an overnight fast compared with wild-type controls [ 57].
The association of low leptin concentrations in the R litters and poor T-maze score suggests that reduced leptin levels may be a mechanism behind the differences seen in cognition.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com