Exact(6)
Therefore, interventions to reduce immobility in the ICU may not decrease the prevalence of long-term impaired muscle strength or physical functioning.
In addition, norepinephrine transporter KO mice have been shown to reduce immobility in the FST and TST [ 44].
Various antidepressants, such as TCAs, SSRIs, and SNRIs, have been demonstrated to reduce immobility without altering locomotor activity [ 18].
Psychostimulants, such as amphetamine and caffeine, also reduce immobility in the forced swimming test with increasing general activity [ 12], so MAK was evaluated for its effects on locomotor activity in the open-field test to exclude a false-positive effect.
Animal studies suggest that estrogen administration can reduce immobility time in the forced swimming test, a paradigm used to test the efficacy of antidepressants and immobility means of depression.
For example, the chronic mild stress procedure was shown to not affect or to increase anxiety-like behaviours, i.e. time spent in anxiety-related areas of the elevated plus maze and dark/light box and to reduce immobility time in forced swimming tests in mice [ 103- 107].
Similar(54)
Indeed, physical activity programs are highly encouraged to prevent contracture and reduce immobility-induced bone loss in patients with OI, but in some patients, the risk of fracture or progression of disease is too great to accomplish meaningful levels of activity.
Compound 32 reduced immobility in a manner similar to the selective 5-HT7 antagoniSB-269970970.
Prenatal morphine exposure also reduced immobility time and increased swimming time in FST.
Results showed that in the FST: 1) pregnancy (P<0.05), or progesterone (P<0.05), or desipramine (P<0.05), reduced immobility by increasing climbing; 2) clomipramine (P<0.05) reduced immobility by increasing swimming; 3) rats tested after delivery displayed similar behavior than control rats.
It also reduced immobility time in forced swim test and time spent in closed arm in elevated plus maze test.
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