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Mammalian muscles display a number of intrinsic alterations during aging (Fig. 2A), which reduce functional capacity together with extrinsic factors (Brooks and Faulkner, 1994; Nair, 2005).
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We hypothesise that undernutrition during early-gestation programmes accelerated ageing through reduced functional capacity; reduced somatic repair; impaired antioxidant systems and initiation of chronic inflammation.
It is hypothesised that undernutrition during early-gestation programmes accelerated ageing through reduced functional capacity; reduced somatic repair; impaired antioxidant systems and initiation of chronic inflammation.
Reduced functional capacity is associated with poor prognosis.
They cause disability and reduced functional capacity, with a substantial penalty in lost production.
Major oesophagogastric surgery is associated with significant postoperative morbidity, reduced functional capacity and quality of life[1].
Health 'shocks' such as unexpected health expenditures, reduced functional capacity and lost income and productivity are primary risk factors for health impoverishment [2, 3].
Critical illness survivors have physical impairment, reduced functional capacity and change in quality of life after discharge from the Intensive Care Unit (ICU).
Skeletal muscle atrophy is a debilitating condition associated with weakness, fatigue, and reduced functional capacity.
Similarly, SO subjects had reduced functional capacity as indicated by walk test and stair-climb test compared to AO group (Figure 1B).
We also measured plasma C-reactive protein (CRP) concentration as an index of inflammation because the concentrations of CRP and pro-inflammatory cytokines in blood have been found to be negatively associated with rates of MPS [30] and may contribute to skeletal muscle atrophy and reduced functional capacity, especially during aging [31] [33].
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