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Similarly, the monoclonal antibody infliximab was shown to significantly reduce fatigue levels in breast cancer survivors with persistent fatigue [52].
The finding that fatigue is linked to the activation of pro-inflammatory cytokines has led to the hypothesis that agents inhibiting these cytokines may reduce fatigue levels.
Finally, any intervention that reduces the incidence and severity of fatigue-inducing side-effects may secondarily help to reduce fatigue levels: this includes control of anaemia, diarrhoea, hypothyroidism, hypophosphataemia, congestive heart failure and malnutrition.
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Reducing fatigue levels by treatment of depression and anxiety should be further explored.
Reduced fatigue levels were experienced in response to paddling and achieving greater fitness, endurance and stamina.
There is less information in patients who have completed therapy, however a single arm study reported that 32 cancer patients, after a 3-week programme of endurance and resistance exercise, had improved physical performance and reduced fatigue levels [ 38].
Some people with MS find ginseng helps reduce fatigue.
Studies show that a green environment can reduce fatigue.
Initiating or maintaining adequate levels of physical activity [ 11– 19], (cognitive) behavioral therapy [ 20– 25], and (psycho) educational interventions [ 20, 25, 26] can reduce fatigue.
Exercise was also mentioned as a means to reduce fatigue.
The recognition that fatigue is a major determinant of the functional status and quality of life of cancer patients and that mild degrees of anaemia contribute to this fatigue, coupled with the demonstration that increasing haemoglobin concentrations can reduce these fatigue levels, has led to an increase in the use of rHuEPO in this setting.
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CEO of Professional Science Editing for Scientists @ prosciediting.com