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In endothelial cells, miR-221 and miR-222 repress proliferative and angiogenetic properties of c-Kit, while hypoxic signals reduce expressions of miR-16, miR-15b, miR-20a and miR-20b, directly targeting VEGF, and supporting the angiogenic process (Poliseno et al, 2006).
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However, XA21-LRR1Ri line 13-6-1 does not reduce expression of LRR1 and did not have reduction in Xa21 transcripts (Fig. 3).
Preliminary research has shown that preoperative metformin administration can reduce expression of tumor markers.
RNA interference (RNAi) technology is one method to selectively reduce expression of a particular gene.
Thus, hypermethylation of GNASXL-DMR would reduce expression of GNASXL.
This way, these SNPs can reduce expression of human genes.
siRNA against Indy/CeNAC2 was used to reduce expression of Indy/CeNAC2.
Clopidogrel will reduce expression of hsCRP and platelet-derived growth factor and also reduce intimal thickness.
Gene silencing was applied to reduce expression of MIF in PBMCs in steroid-resistant patients.
However doxorubicin was able to reduce expression of the anti-apoptotic protein c-FLIP in vivo.
As aforementioned vaccine pressure may drive meningococci to reduce expression of antigens present in the vaccine.
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