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In endothelial cells, miR-221 and miR-222 repress proliferative and angiogenetic properties of c-Kit, while hypoxic signals reduce expressions of miR-16, miR-15b, miR-20a and miR-20b, directly targeting VEGF, and supporting the angiogenic process (Poliseno et al, 2006).
To appreciate how this principle can be applied to reduce expressions, just follow the next example: (1) A ¯ B C + A B C = 1 → A ¯ + A B C = 1 → 1 B C = 1 → B C = 1 Notice that we were able to find a reduced expression which will produce the same output as the original rule for any pattern of input values.
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Starting from overexpression, replicate populations founded by this bacterium all evolved to reduce expression.
However, XA21-LRR1Ri line 13-6-1 does not reduce expression of LRR1 and did not have reduction in Xa21 transcripts (Fig. 3).
Preliminary research has shown that preoperative metformin administration can reduce expression of tumor markers.
RNA interference (RNAi) technology is one method to selectively reduce expression of a particular gene.
Thus, hypermethylation of GNASXL-DMR would reduce expression of GNASXL.
Note that such cross-hybridizations will dramatically reduce expression intensities.
This way, these SNPs can reduce expression of human genes.
siRNA against Indy/CeNAC2 was used to reduce expression of Indy/CeNAC2.
Clopidogrel will reduce expression of hsCRP and platelet-derived growth factor and also reduce intimal thickness.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com