Sentence examples for reduce established from inspiring English sources

Having confirmed that NAMPT expression is increased in CIA, we next investigated if inhibition of NAMPT enzymatic function with APO866 could reduce established CIA.

Antagonism of GM-CSF can strikingly reduce established disease in mouse models of arthritis.

Cesar et al. also discussed the limitations of exercise only to reduce established atherosclerosis.

Increased carrying of the infant has been shown in one trial to prevent crying [ 46] but did not reduce established crying in another trial [ 47].

Imetelstat was also shown to reduce established tumor growth by 35 40 % with a correlation between shortened telomeres and tumor mass (Fig.  4).

In the nineties an antioxidant compound, the liposomal Cu/Zn superoxide dismutase (SOD), was the first drug to half reduce established radiation fibrosis in patients and experimental models (reviewed in [ 3]).

DNase I-activated nanoparticles were not only able to prevent biofilm formation from planktonic bacteria, but they also successfully reduced established biofilm mass, size and living cell density, as observed in a dynamic environment in a flow cell biofilm assay.

Therapeutic losartan treatment reduced established knee joint swelling compared with vehicle control (two-way ANOVA, P < 0.00001; n = 7).

Thus, ADP 355 therapy reduced established tumor growth by 31% (statistically significant, p < 0.05), relative to untreated controls.

Moreover, antagonism of GM-CSF markedly reduces established disease in mouse models of RA and has a comparable effect to that of anti-TNF treatment [ 49].

R788 also delayed disease progression and prolonged survival in NZB/W F1 mice [ 104] and reduced established skin disease in lupus-prone mice [ 105].