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One of the important benefits of the other vaccines used is that as well as protecting vaccinated individuals, they reduce carriage of the bacteria, providing indirect protection to a wider population.
As it is designed to reduce carriage and transmission of Bordetella pertussis, it may hopefully contribute to the ultimate control of pertussis.
For hospitals, their goals are to provide the best products and services to patients and employees, reduce carriage and maintenance cost, improve operational efficiency, and apply advanced technologies to internal (e.g., each department) and external (e.g., customers) functions.
A ship canal was proposed as a way to reduce carriage charges, avoid payment of dock and town dues at Liverpool, and by-pass the Liverpool to Manchester railways by giving Manchester direct access to the sea for its imports and its exports of manufactured goods.
They reduce carriage and induce herd immunity [22], [23].
Ideally, future vaccines would target common proteins to effectively reduce carriage and disease in the vaccinated population.
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When we know how well the vaccine reduces carriage, this might alter the cost effectiveness of the vaccine and make it viable to introduce it for older ages.
Vaccination with the seven-conjugate vaccine against Streptococcus pneumonia has reduced carriage of penicillin-resistant serotypes but not invasive isolates (Karnezis et al. 2009).
Our data, in keeping with previous reports [18], [30], strongly suggest that FnBR peptides are highly effective at reducing S. aureus invasion and might form a novel prophylactic approach to reducing carriage and/or the development of chronic infections.
Several mechanisms might be responsible for the naturally acquired immune response that protects against carriage and reduces carriage density.
For example, respiratory infections are known to be associated with increased acquisition of carriage and antibiotic treatment temporarily reduces carriage.
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