Sentence examples for reduce antibody from inspiring English sources

In addition, the diversity of antibody-related products is increasing including IgG2/IgG4 subclasses and engineered Fc regions to enhance or reduce antibody effector functionality.

However, reduction in size can also reduce antibody avidity [14], and the shortened serum half-life, likely due to kidney clearance and lack of Fc-mediated neonatal receptor recycling, may decrease the overall tumour uptake of these small molecules [15].

Initial histologic and quantitative autoradiography analysis of huA33 showed that uptake in necrotic areas was moderate (0.606 ± 0.493 × 10−3%ID/g), suggesting that intratumoural interstitial pressure may reduce antibody penetration.

Indeed, PEGylation of Sphingomonas sp. A1-III alginate lyase (A1-III), one therapeutic candidate, has been shown to reduce antibody binding in vitro [20].

Patient short-term memory can recover after therapeutic intervention to reduce antibody titer.

Bortezomib, a proteasome inhibitor, was shown to reduce antibody production and reduce vasculopathy in rat cardiac transplantation models [ 111].

The engineering of antibody antigen interactions to reduce antibody-mediated buffering of soluble ligand has also developed into an active area of investigation, leading to novel antibody platforms designed to result in more effective antigen clearance.

It was reported that this molecule targets an early stage of infections and was able to reduce antibody-dependent enhancement (ADE) in vitro.

The functional similarities between HCMV's TRL11/IRL11 and UL119-UL118 productsproducts and FCγR may confer the virus the ability to competitively inhibit IgG binding to the host's FCγR and may thus reduce antibody-mediated effector immune functions.

The α1,6-fucosyltransferase FUT8 catalyzes the addition of fucose on IgG1 antibodies produced by CHO cells which can reduce antibody-dependent cell-mediated cytotoxicity (Niwa et al., 2004; Shields et al., 2002; Shinkawa et al., 2003).

We conclude with a liposomal design that discriminates between healthy and inflamed endothelium while reducing antibody surface presentation.