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The metabolism of these cells is redirected in response to differentiation signals, such as a change in the cell redox state.
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Indeed, resource allocation would be redirected in favour of competition detrimental to pathogenicity.
Though not providing strong specifics, Kullman promised to cut costs and redirect its investments in response to the drop in demand.
A prevailing model is that environmental stress activates mRNA interferases, which then cleave messages to redirect gene expression in response to the applied stress.
Wang and colleagues [17] provided evidence that FAK is a force sensor since FAK-expressing mouse embryonic fibroblasts (MEFs) redirect their migration in response to local changes in matrix tension, while FAK-null MEFs do not.
Plants tend to redirect their metabolism in response to herbivory in ways that affect both the damaged and undamaged parts of the plant [ 36, 37].
Evidently, the down-regulation of genes involved in photosynthesis during the Xcc/kumquat interaction represents a cost for the plant fitness where energy resources were redirected to defence response.
Severing at microtubule crossovers reorients the plant microtubule network and redirects plant growth in response to light.
In conclusion, strategies designed to enhance the immunogenicity and to redirect the cellular response towards a Th1 type response against RON4 could lead to more encouraging results.
In contrast, cross-reactivity between pathogens (or commensals) might redirect the immune response towards suboptimal epitopes or enhance cytokine responses to vaccine antigens, contributing to vaccine-related adverse events.
Finally, we discuss some of the therapeutic approaches designed to prevent cytokine production or in contrast using cytokine to redirect the immune response.
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