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Accordingly, Stx6 knockdown may have caused mis-sorting of internalized GLUT4 myc, leading to its accumulation in perinuclear recycling endosomes that only allow GLUT4 to recycle back to the plasma membrane without proceeding to segregate to acquire insulin responsiveness.
It is also likely that some of them recycle back to the surface because about 10% of them colocalize with the recycling endosome marker TrfR.
Because at some point you run out of options and then you have to recycle back.
One challenge is that the ashes, or oxidized metal, would be hard to recycle back into aluminum without big releases of carbon dioxide.
Choosing the inherently safer option is best accomplished early in the option selection phase of a project; however, recycle back to the option selection phase may be needed if an option is not thoroughly evaluated early in the process.
More interestingly, the internalized LAT1 together with targeting nanoparticles could recycle back to the cell membrane within 3 h, guaranteeing sufficient transporters on cell membrane for continuous cellular uptake.
Similar(28)
First, EGFR can be recycled back to the cell surface through either the recycling endosomes or a direct recycling pathway.
Rab 11, which was used as a recycling endosome (Re) marker, indicated that ∼20% of receptors recycled back to the plasma membrane.
In T. brucei, the TbTfR is recycled back to the flagellar pocket [ 99] in a recycling system that involves two isoforms of Rab5 (TbRandA and TbRab5B), and TbRab11 [ 100].
PS then undergoes normal endocytic recycling such that in the absence of staurosporines, internalized PS is recycled back to the PM by vesicular pathways.
Victims are being recycled back into the trafficking system".
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