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Furthermore we found a trend for improved PFS in primary vs. recurrent situation.
Locally recurrent situation had a significantly negative impact on local control.
Recurrent situation at inclusion was the only factor with significantly negative impact on local control in univariate analysis.
The chosen fractionation scheme depended on the size, number and site of the brain metastases as well as on the 're-irradiation' factor in a recurrent situation.
Reports about the application of carmustine (BCNU), one of the standard chemotherapeutic drugs in the treatment of newly diagnosed glioblastoma, in the recurrent situation are rare.
HfSRT of more than one metastasis was carried out either simultaneously or successively in a primary setting or in a recurrent situation.
Similar(53)
In recurrent situations 56 metastases were treated with a median EQD2 of 38 Gy while in comparison 52 metastases in primary situation were treated with a median EQD2 of 44 Gy.
Since Markov-type models are used in decision problems with time-dependent or recurrent situations [ 21- 24], these were considered inappropriate for this study primarily because asthma was assumed to be a stable diagnosis.
The functions of each module in the DTPO Platform are explained in details as well as the operating mechanism of the platform under both recurrent and non-recurrent situations.
Another interesting research question would be to compare plasma fibrinogen levels before surgery, after surgery, during follow-up, and in an eventual recurrent disease situation.
But in films as superficially different as My Beautiful Laundrette, Dangerous Liaisons and Dirty Pretty Things, he's shown an interest in certain recurrent themes and situations, among them the taking of moral decisions in precarious situations, the secret manipulation of other people's lives and the ironic, usually unintended, consequences of our everyday actions.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com