Compared to species restricted to refugia, such species may have experienced recurrent shifts in their distribution, with populations mixing or separating from each other with the cyclical shrinking or expanding of forests.
Sequences from subject 18 had a recurrent frame shift in the middle of the V3 loop in a string of 6 A's, a known common error in the 454 sequencing process– it was the most common form in the week 02 and week 16 samples from this subject, and is why such drastic cuts were made in those two sequence sets [23].
The physicians in both groups worked at the same university hospital and had on-call duties that involved working recurrent night shifts.
Similarly, these results suggest that repeated shifts in the sleep-wake cycle and the circadian timing system in shift workers may result in recurrent and longer-term changes in circadian period.
Interestingly, in some patients with recurrent disease, a shift from a PN tumor into a MES subtype was observed and is assumed to be induced by therapy.
Variation in parameters of the Earth's orbit around the sun has led to recurrent dramatic climatic shifts throughout its history [1], [2], [3].
For example, geographic variation in the magnitude of the recurrent dramatic climatic shifts during the Pleistocene has been proposed to have exerted a strong influence on extinction and speciation and thus also on current species diversity patterns [19], [20].
More recently, in a large sequence analysis of lung adenocarcinomas, RBM10 was found to be frequently mutated and subject to recurrent nonsense, frame-shift or splice-site mutations (Imielinski et al, 2012).
He said: "Specifically, the 52-59kcal lower total daily energy expenditure on night shifts, if recurrent without a reduction in food intake, would contribute to weight gain.
