Exact(3)
Activation of NMDA receptors in the recurrent pathway may contribute to seizure propagation under depolarizing conditions.
NPY is released spontaneously from recurrent mossy fiber terminals, reduces glutamate release from those terminals by activating presynaptic Y2 receptors, and depresses granule cell epileptiform activity dependent on the recurrent pathway.
Together, however, these mutations all impact JUN signaling activation and encompass approximately 50% of all breast tumors, thus identifying a major recurrent pathway alteration in breast cancer.
Similar(57)
In the neocortex, the link between excitation and inhibition is provided by feed-forward and recurrent pathways [48], [49], [52] [55].
Interestingly, the vast majority of the recurrent pathways we identified involve signal transduction and have been implicated in one or more cancer types.
The Pentose and glucuronate interconversions and Sulfur Metabolism pathways were the most recurrent pathways in the dataset.
The fast emergence of tuning is incompatible with a major role for recurrent pathways that involve lateral connections and feedback connections, since these are associated with additional synaptic and axonal conduction delays.
Such recurrent pathways could also benefit visual form processing if head motion predictive signals were utilized to optimize vision during head turns when minor degrees of retinal image slip and thus defoveation could occur.
While parcellated sensory processing, laminated cytoarchitecture and columnar-like modules are present in the mid- and hindbrains of some fish (Meek 1983; Krahe and Maler 2014), these structures lack the necessary local and long-range feedforward and recurrent pathways associated with information binding underlying phenomenal consciousness (Baars et al. 2013).
The indirect, recurrent pathways that can convey activity from LMAN to HVC (Hamaguchi and Mooney, 2012) provide a substrate over which the consequences of error correction processes in the AFP could be transmitted back to the early stages of the vocal motor hierarchy.
After obtaining stable synaptic responses for at least 15 min, we stimulated the MF CA3 pyramidal cell or the CA3 CA3 recurrent pathways with trains of repetitive stimuli at defined frequencies (0.5 or 2 Hz) for 15 min. The synaptic efficacy was assessed by measuring the peak amplitude of the MF-elicited fEPSP and the radiatum-elicited fEPSP slope (in the middle third of its rising phase).
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