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Recurrent gain of chromosome 17q in human ES cell lines has been reported earlier [28].
Specifically, reanalysis of previously published CxSCC data revealed frequent recurrent gain at 5p.
Recurrent gain of 8q was also detected in our series of vulvar cancers.
A highly recurrent gain on chromosome 17q25.3 was reported in prostate cancer [ 39].
For each group, we preset coordinates of one recurrent gain and one recurrent loss.
Indeed, all human tumor groups showed a recurrent gain on chromosome 8q, likewise all mouse tumor groups showed a recurrent gain on its syntenic region, on chromosome 15, centering exactly on the MYC oncogene.
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Kakiuchi, M. et al. Recurrent gain-of-function mutations of RHOA in diffuse-type gastric carcinoma.
Ma ZY, Song ZJ, Chen JH, Wang YF, Li SQ, Zhou LF, et al. Recurrent gain-of-function USP8 mutations in Cushing's disease.
Recent studies using genomic arrays have shown recurrent gains of the short arm of chromosome 2 (2p) in a subset of CLL.
Recurrent gains at 8q (7%) and 20q (5%) were almost exclusively found in sporadic tumours.
It is consistent with the finding of no specific alterations for MSI tumors, the most recurrent gains in MSI tumors being also observed in MSS tumors.
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