Sentence examples for recurrent driver from inspiring English sources

A general novel driver is a recurrent driver that has not been classified as a driver gene.

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This group has confirmed recurrent driver mutations in APC, TP53, SMAD4, PIK3CA and KRAS, but also found novel therapeutic targets in ARID1A, SOX9 and FAM123B.

We have overlaid recurrent driver mutations (e.g., G/T > A/A) (n = 17) occurring outside of LOH regions (yellow circle, green box) and inside LOH regions (yellow circle, white box).

Yet, even though recurrent driver genes may provide knowledge on what pathways are affected that help tumor cells survive, such driver genes may not always be accessible as targets for treatment.

GRIN2A is a potential rare driver as it is mutated in 1.7% of BRCA patients, but it has been known to be recurrent driver mutation in other cancers [ 77].

This paper proposes a modeling framework able to analyze the alterations in watershed hydrology induced by two recurrent drivers for hydrological changes: climate change and urbanization.

We successfully identified known recurrent drivers, as well as novel patient-specific somatic mutations with high functional potential.

This suggests that it is also unlikely that we have missed additional recurrent drivers of disease, although patient-specific drivers outside the normal patterns of LGSC may exist.

This is what the reviewer understood: it seems that they start out with 202 patients, but only 70 had known highly recurrent drivers.

Some of these correspond to lowly recurrent drivers whose mutational features are not correctly computed because of the scarcity of their alterations.