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Lisa Fain calls these the Tex-Mex trinity, which is a recurrent combination in her "Homesick Texan Cookbook" (Hyperion, $29.99), to be published on Sept. 13.
We have shown quantitatively and qualitatively that recurrent combination of contextual features substantially enhances the initial estimates of local contrast.
These effects might be due to a recurrent combination of adrenergic modulation with the increased residual effect of exercise (muscle and systemic metabolic effects) that promoted increased vascular reactivity.
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Among these, Hidden Markov Modeling (HMM) uses machine learning to discover chromatin states from recurrent combinations of histone modifications, transcription factors and chromatin remodeling factors [ 19, 21].
One powerful example is the appearance of similar mutation patterns (recurrent combinations) in tumors and over human evolution (giving rise to mtDNA haplogroups), which certainly suggests selective constraints (Zhidkov et al. 2009).
We used ChromHMM [ 19] to learn a 15 chromatin state ('cs') model from recurrent combinations, in consecutive 200-base pair (bp) bins, of seven chromatin marks (H3K27me3, H3K27ac, H3K4me1, H3K4me2, H3K4me3, H3K36me3 and the CCCTC-binding factor CTCF) profiled by ChIP-seq [ 18] in preadipocytes on D-2, 0, 3 and 9 of differentiation.
Furthermore, since high expression of these molecules was largely detected in recurrent cases, combination therapy targeted towards these molecules might be promising for clinical application against gastric cancer.
Since recurrent mutations are highlighted there, one can also visually inspect the tree for repeated combinations of mutations.
The ongoing effort to identify effective strategies for the treatment of recurrent GBM includes combination strategies with agents that target complementary or redundant pathways.
Although earlier studies have identified individual predictive factors for recurrent preeclampsia, a combination of variables for the prediction of recurrent preeclampsia has not been explored until recently.
BB is also used in endometrial cancer, in early-stage disease as the sole treatment, and in unresectable and recurrent disease in combination with EBRT [ 6].
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