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Although the Myc protein sequence remains unaltered in most cancers, exceptions occur in the above-cited lymphomas, where over half contain recurrent and often multiple Myc point mutations, which are generally confined to the N-terminal transcriptional regulatory domain (TRD).
Furunculosis is a skin condition which tends to be recurrent and often spreads to family members either directly by skin contact or indirectly.
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Patients are prone to recurrent infections and often suffer from neutropenia, anemia, splenomegaly and autoimmune diseases such as rheumatoid arthritis (RA) and systemic lupus.
This model aims to deliver preventative, early interventions to young people in the hope of avoiding the development of more severe disorders.[53] Schizophrenia and the psychoses are highly disabling, recurrent, and most often lifelong conditions with substantial costs to the patient, their family, and the state arguably greater than almost all other psychiatric conditions.
CADASIL is the most common genetic cause of young-onset vascular cognitive impairment and is associated with migraine, recurrent strokes, dementia, and often psychiatric features including psychosis [ 93].
Acute upper respiratory tract infections (ARI) in children are quite common and often recurrent.
Major depression is a commonly occurring, seriously impairing, and often recurrent mental disorder.
Patients with SCID present with recurrent or severe infections and often with chronic diarrhea and failure to thrive.
Wiskott Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency disorder characterized by the triad of eczema, thrombocytopenia, and severe and often recurrent infections.
Ulcerative colitis (UC) is a chronic non-specific inflammation and ulceration of the digestive tract, involving mainly mucous membranes of the large intestine with serious complications and often recurrent attacks lasting several months to years [ 1].
The life-support skills of flight nurses and paramedics, which are finely honed through regular practice and recurrent training, often far exceed those of ground-based personnel.
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CEO of Professional Science Editing for Scientists @ prosciediting.com