Sentence examples for recurrent aberration from inspiring English sources

For example, a single erroneous interval in only one individual could create two maximal cliques from what should be considered a single recurrent aberration.

Vulval neoplasia samples did not exhibit gain at 5p, a frequent recurrent aberration in a series of cervical tumours analysed elsewhere using an identical protocol.

Our finding was more intriguing, since M-CGH analysis of ACI estradiol-induced rat mammary tumors [ 33], reported similar finding of a recurrent aberration involving proximal gain and distal loss of RNO6 that never occurred in combination with RNO5 loss.

If the random chance of obtaining a proportion higher than actual frequency of genomic aberrations for a given region is <5% (equivalently to 50 times from 1000 permutations), the recurrent aberration for a region was determined to be significant.

We have selected this locus since it is the most prominent recurrent aberration for this dataset and has been previously shown to be a frequent aberration in Prostate Cancer [ 29, 30].

The array CGH profiles detected confirmed several findings from the previous reports of chromosomal imbalances by LOH or metaphase CGH and in addition identified chromosome 5 gain as a recurrent aberration in the LPTA entity.

Combined array comparative genomic hybridization and gene expression studies, as well as whole genome or exome sequence analysis, have now been added to the methods available to screen tumor genomes for recurrent aberrations, gene fusions or aberrant transcripts.

To find recurrent aberrations, we developed a novel parametric test, parametric aberration recurrence test (PART).

We recently published an overview of cytogenetic regions that revealed recurrent aberrations in autistic individuals [4].

Genome-wide quantitative analysis of CNNLOH using the CNNLOH Quantifier method can help to identify recurrent aberrations contributing to tumor development in clinical tumor samples.

Accordingly they aimed for finding recurrent aberrations with high frequencies.