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77% of the patients whose primary tumor samples negatively stained for nuclear p65, showed no recurrence up to 8 years post radical prostatectomy.
There was no recurrence up to the end of the observation period.
Without recurrence up to now (4 years), the finding strongly suggested hydroxyurea as the culprit.
Endoscopic removal of these lesions is associated with high rates of recurrence (up to 60% at three years, depending on the size, number, histological features, and degree of dysplasia [ 1]).
In this experiment, the tumours that qualified as growth-inhibited at 9 days post-vaccination become impalpable and showed no signs of recurrence up to 90 days post-vaccination which categorises them as cured.
This approach suffers from a relatively high rate of incomplete response or local recurrence (up to 50%) with salvage cystectomy being used for failures (Parker and Huddart, 1996; Cooke et al, 2000).
Similar(47)
This seems to be characteristic for CCSK according to smaller earlier reports that describe occurrence of recurrences up to 8 years after initial diagnosis (Kusumakumary et al, 1997).
This is in part due to the high incidence of local recurrences (up to 50%) after surgery despite achieving histopathologically clear resection margins (Jesse and Sugarbaker, 1976; Davidson et al, 1981; Kowalski et al, 1993).
The local regional recurrence is up to 50%, emphasizing the need for wide margins for local control.
The dynamic problem is solved exactly using a recurrence relationship up to any accuracy desired, by deriving the dynamic stiffness matrix for circular and annular membrane elements.
Up to 90% of patients with high grade superficial bladder tumors experience tumor recurrence and up to 50% have progression despite bacillus Calmette-Guerin treatment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com