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For example for the reports of incidence of recurrence studies of special populations such as those of families at increased risk of cancer were excluded.
Recurrence studies replicate the clinical setting with multiple treatment cycles [ 3- 6], while monitoring body weight and tumor volume to report time to elimination of tumors and time to recurrence after cessation of treatment.
Although inconclusive, the results from CRA recurrence studies suggest that folic acid supplementation in individuals at increased risk of CRC on the basis of previous or existing CRA is unlikely to be beneficial for CRC prevention, and could possibly be detrimental, particularly at high doses.
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For the fertility study, any recurrence was ignored and the follow-up continued and conversely for the recurrence study.
Among the 322 cases, 276 cases had complete chart records and meet the requirements of disease recurrence study.
The average tumor volume was much smaller than in the previous GBM recurrence study, with the largest tumor treated at ~5.5 cm [ 8].
Inclusion criteria to participate in the recurrences study were unique P. vivax infection based in microscopy, attendance to controls, adequate treatment response, absence of recrudesce within the first 28 days of following up, and voluntary consent.
Recurrence risk studies can be challenging in other dimensions, including inherent biases, generalizability of findings, inadequate study size, and inappropriate use of analytic models to study recurrence.
Although several patient, tumor, and treatment characteristics have been shown to contribute to locoregional recurrence (LRR), studies evaluating factors related to radiotherapy (XRT) technique have been limited.
With regard to sickness absence recurrence, the studies that calculated sickness absence recurrence rates reported rates that ranged from 7/100 worker months to 80/1000 worker-years.
To investigate CSC properties such as tumor initiation and recurrence, many studies have examined methods for isolation of CSCs from cancer specimens or cell lines.
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