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Furthermore, it is suggested that the mutation of the metastatic phenotype is lower at earlier recurrence sites.
Recurrence sites were in the liver in three cases, lung in two cases, and local recurrence in one case (including overlapped case).
Table 3 > shows the specific recurrence sites.
Relapse occurred in 10 cases (30.3%); recurrence sites were 2 (20%) local and 8 (80%) distant, frequently the bone.
No other differences in recurrence sites with adjuvant trastuzumab were observed (Table 3; Additional files 8, 9, Tables S8, S9).
In 38 recurred cases, most of the recurrence sites were lymph nodes(n = 20) and peritoneum (n = 15).
Similar(46)
Until December 2010, there was no evidence of growth of the neck tumor or new recurrence site observed by CT scan.
Table 2 shows the first recurrence site.
The most frequent recurrence site was the liver (Table 2).
However, tumor markers cannot localize the recurrence site and endoscopy cannot detect extra-luminal recurrence [ 5].
In addition, there were no correlations between nuclear p-mTOR and recurrence site.
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