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We systematically assessed the predictive performance of this method for major clinical outcomes (death, metastasis, recurrence, response to therapy) and the correlation of gene profiling with other clinicopathological correlates of malignant disorders.
Secondary end points included evaluation of disease-free survival (DFS), patterns of recurrence, response rate, and toxicity.
Study endpoints were time to progression (TTP), OS, OS from recurrence, response at 3 and 6 months, and best response.
Identification of biomarkers that accurately predict disease recurrence, response to chemotherapy, and/or prognosis would be of substantial aid in individual risk assessment and treatment selection.
Diagnostic clues such as chronicity, recurrence, response to therapy, and variability in pulmonary function are not available on the first visit or the first few visits.
53 Individual genetic characteristics of the molecular mechanism of the biological clock are involved in the manifestation of mood disorders, including age at onset, risk of recurrence, response to treatment of sleep cycles, and drug treatment.
Similar(53)
The clinical course of these cases was similar to sporadic INS regarding the age of onset, clinical presentation and the presence of minor infection prior to the onset of recurrences, response to treatment and disease outcome.
Clinical tumor recurrence and response was assessed according to the Response Evaluation Criteria in Solid Tumors (RECIST version 1.0) [ 9], by subsequent CT scanning after every two or three courses of chemotherapy.
If RARP would result in an increased local recurrence rate, response rates to SRT could be expected to be better after RARP than after more conventional methods of prostatectomy.
Therefore, there is an urgent need to predict recurrence and response to therapy, especially because patients prone to recurrence may receive alternative treatment.
Outcome variables evaluated included inflammation recurrence, treatment response and decrease in ocular and systemic adjuvant therapy.
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