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Surgery for locoregional recurrence requires extended resection, including adjacent significant organs and vessels to achieve R0 resection, and demands a high degree of skill.
Moreover, local recurrence requires treatment (usually salvage mastectomy) and is associated with anxiety for affected patients.
The analysis of seeding metastases as initial recurrence requires 3 comments.
However, effective elimination of circulating tumor cells, which are indicative of recurrence, requires hepatic macrophages, which depend on CSF1.
Differentiating the nature of recurrence requires that infecting organisms be cultured and typed for both the initial and recurrent episodes of CDI.
For the reasons discussed above, treatment of breast cancer patients in groups with the same risk of recurrence requires further customization, according to the respective molecular subtype of the disease.
Similar(5)
Two patients with recurrence required radiation therapy and 2 patients required a total laryngectomy.
The rate of recurrence requiring redo surgery after primary surgical treatment of varicose veins is between 20 and 30%.
The patient did not experience significant uveitic macular edema recurrence requiring local treatment over the next 2 years.
Frequency of hypoglycemia recurrence requiring repeat ED visits was more common in those taking oral agents compared to individuals taking insulin alone (p = 0.04).
However, even with surgical management, individuals may present with some residual deformity and may suffer from a recurrence requiring further surgery in about 20% of cases [4].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com