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The recurrence of five dinoflagellate taxa in each of the two main branches of the dinoflagellate POR subtree is classic evidence of a gene duplication event (annotated in Figure 3A as GD1).
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He can work out a pattern well enough when he has one: witness his seven-stanza poem, in imitation of Sydney's pastoral, built on a recurrence of six identical rhyme-words.
"When you play football you never get used to your body letting you down, but the positive thing in this injury is that it's not a recurrence of one of his former injuries".
Analysis of the sequences revealed the recurrence of six phages (Table 1).
On the basis of the trees we were able to show repeated within-patient recurrence of two mutations, H1047R and H1047L, in PIK3CA.
One of the most striking results seen is the recurrence of two distinct populations of cells seen in DN, as demonstrated by the bimodal peaks seen in many of the histograms in Fig. 3. Biologically a DN would consist of more than one cell population keratinocytes and melanocytes.
In addition to the BTL cell model, paraffin-derived materials from the primary tumour and one or two recurrences of five further glioblastoma patients were available for analysis.
Although these data are derived from only one cell model, the respective conclusions were also corroborated by the analysis of paraffin-embedded material obtained from primary tumours together with the corresponding recurrences of five additional glioblastoma patients.
Approximately one third of the participants in the study had experienced recurrence of disease – five individuals with local-regional recurrence and one who developed new lung metastases.
Of all cholangitis episodes, 41 (62%) were associated with recurrence of strictures, nine (13%) with recurrent stones and ten (14%) with concurrent recurrence of strictures and stones.
Of note, five patients underwent a second surgery after recurrence, of which four tumours were monogenomic and one was polygenomic in the primary biopsy, which upon recurrence retained their ploidy level (supplementary Table 1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com