The authors raise the intriguing possibility that the choice of hormone regimen may modify the risk for recurrence and account for some of the heterogeneity observed.
The largest excess was for neoplastic-related causes in both relative and absolute terms; recurrences and SPNs accounted for 71.2% and 22.6% of all excess deaths, respectively.
Although recurrence and SPN-related deaths accounted for ∼93% of all excess deaths in both tumour types, there was heterogeneity in the proportion of recurrence and SPN excess deaths; recurrences accounted for 59.0% and 80.2% of excess deaths in osteosarcoma and Ewing sarcoma survivors, respectively, whilst the corresponding excess SPN deaths were 34.7%and13.1%1%.
Although local recurrence and neck lymph node metastases account for most of the deaths from this disease, only 10 20% of patients benefit from the integration of systemic chemotherapeutic therapy, with marginally improved survival and considerable toxic effects [2], [3].
In these two studies, physical activity also tended to be associated with reduced risk of both recurrence and breast cancer death, which accounted for the majority of deaths.
For example, our model accounts for cancer recurrence, and the time until reappearance of the tumor crucially depends on the heterogeneity of the transmission coefficient (Fig. 2).
An alternative factual account of eternal recurrence and time consonant with Hatab's literality criterion would not circumvent the existential imperative of the "selective principle". The moments of becoming since Kant's dynamical theory at least warrant in-depth investigation (as Hatab on occasion acknowledges).
One article reported time to relapse to account for disease recurrence and the rest used recurrence rates.
These findings indicate that B7-H4 positive tumor stem cells may account for tumor recurrence and T-cell inhibition.
Hepatocellular carcinoma (HCC) has been known as one of the most lethal human malignancies, due to the difficulty of early detection, chemoresistance, and radioresistance, and is characterized by active angiogenesis and metastasis, which account for rapid recurrence and poor survival.
