Suggestions(2)
Exact(2)
These include adequacy of study design (prospective cross-sectional, observational, and randomized controlled trial with an adequate control group); recruitment of sample; ascertainment of depression and IR; and control for cofounding variables, such as age, sex, socioeconomic status, and BMI.
Feedback from patients suggested that the wording of two items was somewhat ambiguous and these were subsequently changed prior to the recruitment of sample 2. Participants were 547 consecutive cancer patients (average age 66.5 yrs (SD = 14.5), 304 women and 243 men) coming into first contact with the Fraser Valley Cancer Centre (i.e., after a positive diagnosis had been established).
Similar(58)
A fundamental challenge in scale development with low prevalence populations such as BD is recruitment of samples of sufficient size given that psychometric research generally requires 200 300 participants (Clark and Watson 1995).
Recruitment of samples included in this study has already been described [ 11].
Research fellows situated within the CPS will be in charge of recruitment of Samples 3 and 4.
Recruitment of samples was limited by two main factors: (i) Maya linguistic diversity and their reservation towards medical study participation, and (ii) logistical difficulties for DNA sampling in a partially rough terrain with very difficult access.
Limitations of lower quality studies included measuring but not reporting socioeconomic group differences for all outcome measures, leaving a long period of time between cancer diagnosis and participation in the study and recruitment of samples biased towards higher socioeconomic groups.
We used purposive sampling to facilitate the recruitment of a sample reflective of a range of demographic characteristics.
The appraisal indicated that the evidence-base presented with a number of methodological limitations, most strikingly the recruitment of small sample sizes with insufficient power (Tables 4, 5).
The ability to use non-neuronal tissues to explore transcription in neuropsychiatric disorders is of heuristic value, allowing the recruitment of larger sample sizes.
First, its main limitation lies in recruitment of the sample.
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