Actually, as discussed below (see "General considerations and implications"), recruitment and maintenance of BubR1 at kinetochores might involve different mechanisms.
On the other hand, association of BubR1 to metaphase kinetochores appears to depend strongly on kinetochore assembly, as it is strongly destabilised in CenH3CENP-A-depleted DT40 cells [30], suggesting that initial recruitment and maintenance of BubR1 at kinetochores involve different mechanisms and, perhaps, fulfil different functions.
It is well known, however, that healthy canopies exert a strong control on the physical and biological environment, for example by sweeping away detrimental sediments or inhibiting potential competitors such as algal turfs [21], [47], [48], thus triggering positive feedbacks that facilitate self recruitment and maintenance [23].
The treatment of severe hypoxemia in ARDS is highly dependent on the recruitment and maintenance of lung volume [ 21, 22].
Arrow thickness reflects the relative strength of the recruitment or maintenance, and the size of the text reflects the amount of protein localized at centrosomes.
This is also a reasonable mechanism for the recruitment and maintenance of water molecules important for hydride tunneling as required for catalysis.
Together, these data suggest that multiple ISWI chromatin-remodeling complexes act during DSB repair, probably to allow efficient recruitment and maintenance of repair proteins and signaling events.
Alveolar recruitment and maintenance of lung volume are important goals in the treatment of acute lung injury (ALI) and essential for improving oxygenation.
Here, we report that β-III spectrin is essential for the recruitment and maintenance of ankyrin R at the plasma membrane of Purkinje cell dendrites.
