Exact(2)
The list of recruitment errors is as long as their premiership drought – 28 years and counting.
For as Wray freely conceded, the wasted years, the costly recruitment errors and the flawed coaching appointments made this success all the sweeter.
Similar(58)
In contrast McDonald et al. (2011) attributed the observed increased mutation rate to the recruitment of error-prone DNA polymerases at stalled replication forks due to repetitive sequences (but see Jovelin and Cutter 2013 for review).
Mammalian BRCA1 promotes HR at sites of DSBs during S/G2 phase by suppressing the recruitment of error-prone nonhomologous end joining (NHEJ) (Chapman et al. 2013; Escribano-Díaz et al. 2013).
Guanine-6-sulphonate is a severe block to replication and may require the recruitment of error-prone DNA polymerases to effect bypass (O'Donovan et al, 2005; Zhang et al, 2007).
In their model, McDonald et al. (2011) associated the increased mutation rate within the flanking sequences of microsatellites to the recruitment of error-prone DNA-polymerases at stalled replication forks.
These results are compatible with the combined effects of previously proposed mechanisms of indel-associated mutation (De and Babu 2010; McDonald et al. 2011), suggesting that repeat sequences encourage indel formation, with subsequent recruitment of error-prone polymerases that incidentally create single nucleotide mutations during DNA repair.
Both process (recruitment) and observation errors were considered.
Steps include the relevance of research questions and study objectives; sampling strategy and addressing error; recruitment and participant management; structuring interviews and asking the right questions; validity and reliability; practical tips for before, during, and after the interview; and technical considerations.
If theorically mutagenic mismatch repair in the absence of DNA replication does not require a specialized DNA polymerase, the high rate of mutation observed during SHM is achieved by the recruitment of specialized error-prone DNA polymerase [23], [24].
But we have also made errors in recruitment, mistakes we have immediately tried to address in January.
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