These studies have demonstrated that different executive functions not only recruit various frontal areas but also depend upon posterior (mainly parietal) regions.
They act as a primary barrier to the diffusion of solutes through the intracellular space, create a boundary between the apical and the basolateral plasma membrane domains, and recruit various cytoskeletal as well as signaling molecules at their cytoplasmic surface.
TCR clusters recruit various cytoplasmic molecules, such as LAT, Zap70, and SLP76, which carry out downstream T cell signals [4], [5], [6], [7].
MBD-containing proteins (MBPs) recruit various chromatin-modifying complexes to methyl-CpG sites to bring about further changes in chromatin structure: prototypically those associated with nucleosomal compaction and transcriptional silencing.
We previously showed that Barx2 contains both an N-terminal repression domain and a C-terminal activation domain [36] that may recruit various co-repressors and co-activators respectively.
Depending on its ability to recruit various scaffold proteins [50], JIP could also increase the JNK susceptibility to Ser/Thr- and/or Tyr-phosphatase activities associated to the C-terminus of LRP-1 [38], [51], [51].
