Cannabis and other drug use was rated with the Alcohol and Drug Use Scale [ 22] which records severity (1 = abstinent, 2 = use without impairment, 3 = abuse, 4 = dependence) and frequency of use (0 = no use, 1 = once or twice per month, 2 = 3-4 times per month, 3 = 1 2 times per week, 4 = 3 4 times per week, 5 = almost daily) in the last month.
Injected skin was photographed to record severity of erythema and edema.
We also recorded severity of the ADRs according to the Hartwig severity scale [20], which was adapted from our pilot study [11], and subsequently modified to include two level 7 ADRs in order to differentiate between ADRs which directly, and those which indirectly, cause death.
Furthermore, none of the care homes recorded severity of dementia in their care notes.
These questions have previously been used in recording severity of symptoms in patients with irritable bowel syndrome (IBS) [ 10].
None of the care homes recorded severity of dementia in their care notes but behavioural and communication difficulties arising from having dementia were recorded.
Patients recorded severity of pain while being tested by giving a report mark ranging from 0 'no pain' to 10 'severe pain'.
Participants were instructed to complete diaries to record severity of common cold and chest (asthma) symptoms and peak expiratory flow rate (PEF, using a MiniWright meter, KW-Med Inc., USA) twice a day as previously described [ 24].
It records the severity of symptoms on a qualitative scale with 7 levels, ranging from 'absent' to 'very serious'.
For each AE, investigators recorded the severity (mild, moderate, and severe), relationship to the study product (unrelated or unlikely, possibly, probably, or definitely related), and treatments for each event.
The original ICF qualifier is used to record the severity of the problem: no problem; mild; moderate; severe; or complete problem (included in the codes are qualifier 8 (not specified) and qualifier 9 (not applicable)).
