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We recorded protocol deviations whenever a pre-, intra-, or post-operative dose was missed, given incorrectly, or supplemented with additional non-study antibiotics.
It was not possible to determine the end of follow-up for over 15% of primary research projects, and over 18% of the evidence synthesis studies did not have a recorded protocol online date, so they were not included in the analyses.
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Limb movement was controlled by the experimenter and was held still or passively moved during the various recording protocol segments.
GG has been involved in the conception and design of the animal recording protocol, in the analysis and interpretation of data as well as in revising the manuscript.
There had also been a wide variety of recording protocols and methodologies employed for data analysis [ 53].
This is unlikely to cause bias, since we used well-defined treatment and recording protocols for all animals.
Recording protocols were delivered via Igor Pro software (Wavemetrics) in conjunction with Nclamp (Jason Rothman, University College London, UK, see http://neuromatic.thinkrandom.com ).
All recording protocols, except for the gap-free recording in current clamp, were applied below 0.1 Hz to eliminate potential short-term plasticity effects.
Owing to data recording protocols, confidentiality regulations, and to eliminate minor incidents, only cases with an injury severity score (ISS) 25 greater than 15 were included.
Using this HFS and recording protocols, both experimental groups presented a significant LTP for the first 24 hr [ P < 0.001; F(24,216) = 10.785], but with some interesting differences between them.
Analyses were conducted using three exposure periods: the hour during the recorded HRV protocol and the 4- and 24-hr mean before the HRV protocol.
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