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Both Cranney and Chung used the WHI and RECORD studies in their analysis.
A systematic review of retrospective record studies found the proportion of highly preventable AEs in patients with an UIA between 17% and 77%.
8 9 10 This issue prevented the pooling of data on major bleeding reported in the publications of the RECORD studies.
Unlike clinical record studies, the Diabetes Prevention Program trial targeted people who were at high risk of diabetes because of overweight and elevated blood glucose levels (10).
Although judgement of presence of AEs is difficult, retrospective patient record studies currently offer the best method available to assess incidence of AEs[ 23].
However, as a result of the RECORD studies, cases of VTE events can be avoided with rivaroxaban, which reduces hospital expenditure.
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Dr. Marciniak's review of the Record study calls that assertion into question.
So Dr. Marciniak took an unusually close look at the Record study, demanding to see records that the agency rarely examines.
For the analysis we used a combination of observation, interviews, and patient record study.
Participants (n = 759) in the multicentre RECORD study were studied.
The RECORD study sponsor is GlaxoSmithKline, the manufacturer of rosiglitazone.
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