Sentence examples for reconstruct regulation from inspiring English sources

To evaluate the ability of PMN to reconstruct regulation pathways, we used a test case in which the regulators and the modules are known.

Another compelling alternative is to avoid the clustering step and reconstruct gene regulation networks by modeling expression values directly.

We have analyzed the genomes of all species belonging to the taxonomic families Bacillaceae, Listeriaceae, Staphylococcaceae, Lactobacillaceae, Leuconostocaceae and Streptococcaceae to determine the diversity in central nitrogen metabolism and reconstructed the regulation by GlnR.

These methods are able to reconstruct many gene regulations which have been previously detected using wet-lab experiments, for example, in Escherichia coli.

Contact: [email protected] The development of methods that allow us to uncover mechanisms of gene regulation and reconstruct gene regulatory networks is an important open problem in molecular biology.

While many methods have been introduced to reconstruct first-order gene regulation (e.g. DBN-MCMC [ 1- 3], dynamic RandomForest [ 4]), there are only a few methods for inferring time-delayed GRN.

Thompson et al. have measured mRNA profiles in 15 different species of yeast and reconstructed how the regulation of groups of genes (modules) have evolved over a period of more than 300 million years.

Since the release of complete sequence of P. putida KT2440's genome, metabolic networks of the P. putida KT2440 have been reconstructed and the regulation mechanisms of various potential enzymes have been disclosed.

All this information was used to reconstruct the architecture of CtrA regulation throughout the phylogenetic tree of alpha-proteobacteria to reveal evolutionary trends and insights into this complex regulation.

Approaches that use these data to reconstruct the network of genetic regulation and to define its parameters include approaches that use Bayesian networks [ 17- 20] and ones based on mutual information [ 21, 22].

It remains a grand challenge to integrate all these regulation layers together to reconstruct a holistic stress response network.