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We did this by investigating the departure from a null model capturing the number of codivergent events in the assemblage of reconciled trees for both DdDp and core-less genomes.
Reconciled trees represent the most informative grouping strategy.
Reconciled trees were benchmarked to the hierarchical reference groups.
Extended orthology/paralogy relationships were obtained directly from the reconciled trees.
Reconciled trees are an attempt to resolve incongruence between gene and species trees by predicting gene duplications and losses [ 64].
Reconciled trees were further checked to account for possible biases in the phylogenetic tree reconciliation method as reported in Hahn et al [ 26].
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Gene duplication and losses have been inferred from a reconciled tree, reconstructed by combining information from gene tree and species tree.
Modifications of basic reconciliation methods, embodied in TreeMap 1.0 and TreeMap 2.02, represent the addition of weighting schemes in which the researcher specifies allowed departures from cospeciation a priori, with the result that TreeMap results more closely agree with BPA results than do reconciled tree analysis results.
The reconciled tree method was applied to the 35 phylogenetic trees.
To estimate these numbers, we used the reconciled tree method [37] [39], in which the topology of a gene tree is reconciled with that of a species tree.
In order to root our tree, we used a combination of likelihood comparisons, reconciled tree analyses and parametric bootstrapping (summarized in figure 3 and described in Methods).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com